Aromatherapy _ basic mechanisms and evidence-based clinical use

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Aromatherapy is a specialized form of phytotherapy that uses essential oils extracted from diverse parts of aromatic plants more often delivered via inhalation or massage for several minor clinical uses. Essential oils are phytocomplexes made up of several components endowed with a broad spectrum of biological activities, some of which have been deciphered only recently.
A PubMed search on April 13, 2015, using “essential oils” as the keyword phrase resulted in 13,844 articles dating back to 1880, the year of the first article published by H.C. Wood and E.T. Reichut in the prestigious Journal of Physiology: “Note on the Action upon the Circulation of Certain Volatile Oils.” The reading of this article has an obvious historical meaning, though it anticipates the experimental complexity in studying such phytocomplexes, starting from the important, and not so obvious, qualitative differences in their biological effects in living animals, emerging by changing their route of administration.

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