Pharmaceutics_ Basic Principles and Application to Pharmacy Practice (2013)

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Pharmaceutical education in the United States of America has been undergoing substantial changes over the past several decades to address changes in a pharmacist’s role in the provision of pharmaceutical care. Pharmacy education has had a historical perspective that prepared student pharmacists to engage in pharmaceutical dispensing or pursue graduate pharmaceutical education focused on research. Any clinically-focused education was then obtained through post- baccalaureate training and experience. The currently evolving perspective of pharmacy education is focused on preparing student pharmacists as providers of clinical pharmaceutical care and as the medication expert in the healthcare system. These evolutions have increased the need for pharmacy education to be solidly-grounded in scientific principles. Key domains of pharmaceutical knowledge include: medicinal chemistry and pharmacology for an understanding of drug molecule properties and mechanisms of action; pharmaceutics and biopharmaceutics to utilize physicochemical properties of drugs to develop a safe, effective and reliable drug product and their interactions with human physiology; pharmacokinetics and pharmacodynamics to explain drug movement and pharmacologic effects within systems; pharmacy practice to interpret the role of medications in the diagnosis, treatment, and prevention of disease; and social and administrative studies to evaluate health services and patient safety. Pharmaceutical education should substantively address all of these domains to provide scientific foundations for rational clinical decision making. Additionally, only pharmacy education can provide the scientific depth and breadth across these various levels of knowledge domains.


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