Inhibitors of Monoamine Oxidase B (1993) Pdf Free Download

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Drug development is one of the most exciting, yet sometimes frustrating enterprises in the world. Inter alia, it requires intuitiveness, attention to detail and the ability to interpret preclinical data in terms of their clinical practicability, even if the clinical efficacy decides their definite fate.

Monoamine oxidase inhibitors are typical examples of such an exciting development with the inherent "ups" and "downs". About 40 years ago, monoamine oxidase (MAO) inhibitors were recognized as therapeutic agents for the treatment of depression. Despite promising results with the first generation of MAO inhibitors, their benefit was overshadowed by serious side-effects. The relatively young MAO research sustained severe set-backs. In fact, in the late 1960s very little was heard about MAO research. 

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