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This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the nuclear magnetic resonance approaches are described in the chapters authored by David S. Wishart and co-authors, G. A. Nagana Gowda and Daniel Raftery, and Ryan T. McKay. Advances in mass spectrometry are covered by Charles R. Evans and co-authors and Stefan Kempa and co-authors. This book also reflects the state of the art in the application of metabolomics to cell biology (Ulrich L. Günther and co-authors) and chapters that share insights into the application of metabolomics. These include the assessment of treatment response (Paola Turano and co-authors) and the phenotyping of various diseases (Rachel S. Kelly and coauthors, Paige Lacy and co-authors, and Angela J. Rogers and co-author). Relationships of metabolomics and drugs are highlighted by Robert Verpoorte and co-authors, Oscar Millet and co-authors, and Daniel L. Hertz and co-author. Given the diverse topics addressed, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
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