Pharmacology of Central Synapses (1980) Pdf Free Download

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THE author and his collaborators have shown in their numerous investigations that the action of neurotropic drugs is based on their influence on synaptic transmission. The present monograph is concerned with this aspect of their mode of action. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological and biochemical findings, form the conceptual basis of this monograph.

The use of new methods, such as electron microscopy, histochemistry, autoradiography, differential centrifugation, techniques involving intracellular electrodes, and microiontophoresis, for the investigation of the structure and function of synapses has greatly contributed to our understanding of the pharmacology of the central nervous system. The interpretation of the results obtained by the author and his collaborators has naturally taken into account the scientific achievements in relevant fields throughout the world.

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