Pharmacology of Endogenous Neurotoxins (1998) Pdf Free Download

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"Since the discovery of MPTP .... " These introductory words appear at the beginning of a voluminous literature published by neuroscientists who are dealing with MPTP and the neurotoxicological aspects in pathogenesis of Parkinson's disease. Although many biochemical parallels do exist between Parkinson's disease and MPTP-induced parkinsonism, it should be clear that patients with idiopathic Parkinson's disease had never ingested MPTP in their lifetime. However, the nucleus of MPTP responsible for its toxicity is a common chemical moiety and thus, may occur in many other substances

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