The Biostatistics of Aging (2014) Pdf Free Download

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The purpose of this book is to describe a new quantitative method to examine the relative contributions of genetic factors and lifetime exposures to rates of mortality and disease incidence in a population. The book is highly multidisciplinary. The theoretical foundations of the work presented here involve the fields of statistics, evolutionary biology, demography, and epidemiology and should be of interest to those in these fields. Moreover, in its applications the work is broadly relevant to medicine, aging, and public health. Researchers and practitioners in these areas are also target audiences. We expect readers to comprise a spectrum from the more mathematically inclined to the more biologically inclined, though of course there will be readers who have expertise in both domains. This made the choice of level of presentation especially difficult. We chose to tilt the balance in favor of reaching a wide audience, at the cost of possibly making some (though hopefully not all) of the material in a field seem basic for an expert in that field. We also endeavored to make the book more widely appealing by keeping the denser mathematical material in a separate section in Chapter 2 and in a few appendices, and by providing summary pictures and statements after a series of mathematical results and at the end of some elaborate arguments. We bring the results and arguments from different areas of knowledge together starting in Section 2.2.1, and we hope the reader’s forbearance will be rewarded with some interesting synergies.

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