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Antibodies are natural inhibitors of pathogens produced by B lymphocytes. The in vivo biological process involving antigen presenting cells, T and B lymphocytes necessary for their production are not addressed in this book, but can be found on any immunology text book.
The breakthrough study by Kohler and Milstein was the ability to produce in vitro antibodies by cell fusion. This finding catapulted the use of antibodies as therapeutic agents. With the emergence of recombinant DNA technology and the innovative ingenuity of scientists, these magic bullets are now continuously being developed both for research and therapeutic purposes by a myriad of techniques and their use in many clinical conditions are a testimony of their importance. This book provides examples of these developments and the current areas of further research and improvements.
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