Advances in Pharmacology and Chemotherapy - Vol 13 (1975) Pdf Free Download

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Human Chagas’ disease has been affecting people from nearly all countries of the American continent, from the South of the United States to Argentina and Chile. The prevalence of the disease in the different countries has been roughly estimated as occurring in 20% of the whole population, which means that, at least, 7 million people are infected with Trypanosoma cruzi (World Health Organization, 1960). Vectors have been found in large areas of the neotropical region, from the 43rd parallel north to the 49th south latitude. Trypanosoma cruzi-like trypanosomes have been detected in more than 100 mammalian wild species, belonging to several orders, in endemic regions and in areas apparently free of human Chagas’ disease. About 35 millions inhabitants are probably exposed to the risks of infection in all endemic area.

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