Vaccine Development_ From Concept to Clinic (2022) Pdf Free Download

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A vast body of clinical experience has supported the introduction of several vaccines for routine use across the globe, resulting in a dramatic impact on public health. Research and development efforts continue to translate this impact and find scientific and novel technological innovations to target many diseases to address unmet medical needs. SARS-CoV-2 represents a new historical milestone in vaccine design and immunotherapeutic strategy development achieved at breakneck speed. The COVID-19 pandemic demonstrates the need for groundbreaking cross-disciplinary research efforts in immunology, vaccinology, infection, and epidemiology. It is important that vaccines meet various regulatory requirements for safety, stability, quality, and efficacy. The primary motivation of this book is to provide a comprehensive forum for the presentation of various components that define the development and control strategies to produce safe and stable vaccines that elicit consistent and robust immunogenic responses. The book aims to cover the landscape comprising preclinical safety considerations, clinical trial design and development, high-throughput clinical assay development, mechanisms of vaccine adjuvants, process development, and also several aspects pertaining to the chemistry, manufacture, and control (CMC) of vaccines.

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